12.00 – 18.00
Registration
13.30 – 14.00
Welcome Coffee
Cortile del Settecento
14.00 – 14.30
Opening Session
Aula Magna, Via Festa del Perdono 7
Chiara TONELLI
,
FISV President
Monica DILUCA
,
Vice Rector for Research and Technology Transfer University of Milan
14.30 – 15.15
FISV Lecture
Aula Magna, Via Festa del Perdono 7
Elena CATTANEO
,
University of Milan and INGM Milano
Huntington: the journey from gene sequence to neuronal damage
15.15 – 16.00
FUV Lecture
Aula Magna, Via Festa del Perdono 7
Franco LOCATELLI
,
Children’s Hospital Rome – Catholic University of the Sacred Heart Rome
CAR-T cells: from consolidated indications to the future applications in different diseases
16.00 – 18.00
SYMPOSIUM 1: Chronobiology: biological rhythms and their effect on living organisms
Aula Magna, Via Festa del Perdono 7
Chairs: Fiorella LO SCHIAVO, University of Padua
Rodolfo COSTA, University of Padua
Mariano PERALES
,
Polytechnic University of Madrid
Molecular mechanisms linking the circadian clock to tree seasonality
Paolo Maria TRIOZZI
,
Sant’Anna School of Advanced Studies
Oxygen: a missing input for the plant circadian clock?
Gian Michele RATTO
,
CNR, Italy
Intracellular chloride as a signalling hub linking the autonomous circadian clock with neuronal excitability
Nazareno CAPITANIO
,
University of Foggia
The Rhythm of Life: Intertwining Mitochondrial Metabolism and Circadian Clock-Genes in Health and Disease
18.00 – 19.00
Apericena
Cortile del Settecento
19.00 – 21.00
MINI-SYMPOSIA
MS1: Enviromental, evolutionary and developmental biology
Via Festa del Perdono 7 – Room 433
Chairs: Andrea SCHUBERT, University of Turin
Anca MACOVEI, University of Pavia
Alessia AMETRANO
,
IBBC-CNR Naples
Simulated marine heatwaves reveal epigenetic regulation of the polymeric immunoglobulin receptor gene in Antarctic teleosts
Emanuele BOSI
,
University of Genoa
The resistome of European coastal environments revealed by high-resolution targeted metagenomics in oysters
Valerio FOSCHI
,
Roma Tre University
Modulation of thermospermine metabolism alters xylem architecture and drought resilience in Solanum lycopersicum plants
Flavia GRECO
,
University of Turin
Space worms: adaptation to microgravity and low magnetic field strength
Benedetta PIZZICONI
,
Campus Bio-Medico, University of Rome
Polystyrene nanoplastics uptake and genotype-dependent responses in durum wheat: from hydroponic to soil-grown systems
Ruihan SHEN
,
University of Turin
KAI2 receptors shape the response to nitrogen limitation and nitrogen use efficiency in tomato
Emanuele CAPRA
,
IBBA-CNR Lodi
PFNA exposure disrupts sperm function and reprograms the epigenome in male rats
MS2: Genetics, epigenetics and chromosome biology
Via Festa del Perdono 3 – Room 104
Chairs: Giuseppe MERLA, University of Naples Federico II
Rossella TRICARICO, Univerisy of Pavia
Vittoria BRAMBILLA
,
University of Milan
Stem growth in rice is controlled by chromatin remodelling that promotes cell division at the intercalary meristem
Erika CASARI
,
University of Milano Bicocca
Activation of MRX endonuclease by the Sae2 C-terminus: functional and molecular insights
Martina GRECO
,
University of Trento
The intranuclear protein quality control pathway sequesters excess histone H3 variant Cse4 to prevent chromosomal instability in budding yeast
Anna PISCONE
,
University of Naples Federico II
XRCC1 deficiency promotes telomeric chromatin leakage, inflammatory signalling and senescence
Erica ROSSI
,
University Roma Tre
Telomerase reverse transcriptase as a modulator of mitochondrial DNA and mitophagy
Martina SANTULLI
,
University of Bologna
YEATS2 defines an E2F3-associated function of the ATAC core complex
Esi TACI
,
University of Milan
Exploring the link between cellular senescence and neurodegeneration using iDISCO on brain organoids
MS3: Genomics, proteomics and systems biology
Via Festa del Perdono 3 – Room 109
Chairs: Candida VANNINI, University of Insubria Varese
Michela ZOTTINI, University of Padua
Alessia CANEVOTTI
,
University of Milan and CNR-IBIOM, Bari
An integrative evidence framework and interactive resource for annotating the human pre-miRNA repertoire
Guido DOMINGO
,
University of Insubria
Small peptides, big defense: chloroplast non-conventional peptides as novel regulators of thermal stress
Margherita FERRETTI
,
IRCCS National Cancer Institute Regina Elena Rome
Spontaneous miscarriage reveals CD47-SIRPa axis as a targetable immune checkpoint in endometrial cancer
Sophia LUCHE
,
University of Parma
Functional dynamics: metabolomic exploration of perennial wheat roots and their interacting microbial ecosystem
Marcello MANFREDI
,
University of Piemonte Orientale
Unraveling CSF protein complex networks in neurodegenerative diseases
Emanuela PEDRAZZINI
,
IBBA-CNR Milan
Lysine deserts in seed storage protein evolution
Davide PEZZINI
,
University of Pavia
Multi-omics approach to investigate the impact of seed coat pigmentation on Trifolium alexandrinum germination
19.00 – 21.00
POSTER PRESENTATION
P4: Current trends in biotechnology
Via Festa del Perdono 7 – Room 435
Chairs: Elisa CLAGNAN, University of Milan
Eleonora COMINELLI, CNR-IBBA, Milan
Giulia ANDERLUZZI
,
University of Milan
The effect of cationic polymer on the structure and pDNA transfection efficiency of lipopolyplexes
Giacomo BIRRO
,
University of Verona
Primed for stress: loss of Aucsia2 improves salt resilience in tomato
Michela BRUSCHI
,
University of Urbino Carlo Bo
Thiol-based compound hinders Pseudomonas aeruginosa pyocyanin redox cycling and dampens LPS-driven acute pulmonary inflammation
Simona COMPARATO
,
Istituto Nazionale Oncologico Candiolo
Exploring the expression pattern of LINE-1–derived chimeric transcript of MET (L1-MET) across different tumor types
Marco DAINELLI
,
University of Florence
Constitutive metabolic adjustments underlying thallium hyperaccumulation in Silene latifolia
Francesca GIANNESE
,
Human Technopole, Milan
The National Facility for Genomics of Human Technopole: Supporting Population Genomics Research and Technology Development in Italy
Giovanni MESSINA
,
Link Campus University, Rome
Setting up of an in vitro model to investigate the effects on cell metabolism induced by the photobiomodulation protocols used for plantar fasciopathy
Pietro ROVERSI
,
CNR-IBBA, Milan
Structural Basis of ERAD-L Commitment by an EDEM:PDI Checkpoint Complex
P5: Food and sustainable nutrition
Via Festa del Perdono 7 – Room 517
Chairs: Stefania MASCI, University of Tuscia
Costanza CECCANTI, University of Pisa
Emma BERTOLE’
,
University of Milan
Set up method for assessing the amount and activity of wheat germ agglutinin lectin
Lorenzo BRUSETTI
,
Free University of Bolzano
Irrigation water quality drives antimicrobial resistance co-selection along the Adige Valley: preliminary findings from the AppleHealth project
Beatrice CHIAVACCI
,
University of Florence
Crops that inherit their stress memories: Cicer arietinum against salt stress
Elena DE AMICIS
,
University of L’Aquila
Microalgal bioactive compounds as natural elicitors for sustainable crop protection
Noemi DI VITA
,
University of Padua
Proof of concept for RNAi-based weed control in Solanum nigrum
Ridwan DIAGUNA
,
University of Pavia
Screening for heat stress tolerance in tomato: Impact on seed repair response
Alessandra MARINELLI
,
University of Milan
Anthocyanins as a possible strategy to protect against mycotoxin toxicity
Andrea PAGANO
,
University of Pavia
Synergies in seed quality research to enhance stress tolerance in model and orphan legumes
Maria Manuela RIGANO
,
University of Naples Federico II
Effect of combined shade and drought stress on a S. pennellii introgression line.
Marta TOCCACELI
,
University of Milan
Purple corn anthocyanins encapsulated in zein nanoparticles and their role against inflammatory bowel diseases in vitro
P6: Health and disease
Via Festa del Perdono 7 – Room 515
Chairs: Franco FAORO, CREA-IT
Elena Bianca DONETTI, University of Milan
Giulia Luna BERGANTINO
,
University of Sannio
Selection of DNA aptamers targeting psoriasis-associated CARD14-mutant keratinocytes
Stefano BIRESSI
,
University of Trento
Reduced fibrosis after in vivo inhibition of complement C1 in animal models of Duchenne Muscular Dystrophy
Ludovica CAPONE
,
University of Sannio
Disruption of macrophage CBM complex signaling impairs adipocyte metabolic homeostasis in vitro.
Rosita DI PALMA
,
University of Naples Federico II
Targeting oxidative and ER stress to improve chemotherapy in lung cancer cell: the adjuvant role of olea europaea in lung cancer
Chiara DONATI
,
University of Pavia
Novel Riluzole-derivative VA942 affects voltage-gated sodium and potassium currents expressed in SH-SY5Y-derived neurons
Nicole MARCATI
,
University of Parma
Parallel Evolution of a GLP1R Residue in Mammals and Humans Reveals a Pharmacogenomic Determinant of GLP‑1 Receptor Agonist Response
Valentina MARGARITA
,
University of Sassari
Sex-based differences in prenatal innate immunity: divergent foetal responses to Mycoplasma hominis infection between males and females
Francesco ACQUATI
,
University of Insubria
Role of the human RNASET2 gene in the pathogenesis of Aicardi-Goutières syndrome.
Shirin NAVACCI
,
Sapienza University of Rome
AMBRA1 regulates Sonic Hedgehog signaling during cerebellar development and promotes SHH-medulloblastoma
Roberto OLEARI
,
University of Milan
Connecting craniofacial malformations with neural crest splicing defects by defining the role of nuclear cyclophilin NKTR
Zeudi PETRONE
,
University of Naples Federico II
Modelling diabetic corneal injury in ovo: a rapid platform for testing bioactive ophthalmic formulations
Gabriele SALES
,
University of Padua
Self-supervised learning reveals mutation-specific morphological signatures in Gaucher disease fibroblasts
Davide SARTINI
,
Marche Polytechnic University
Therapeutic potential of paraoxonase-2 enzyme in triple-negative breast cancer treatment
Chiara SCAPOLI
,
University of Ferrara
Recurrent pregnancy loss and smoking share CTNNA2 rs4852592 locus effects through independent pathways
08.30 – 10.30
PARALLEL SYMPOSIUM 2: Microbiome Modulation Across Systems: Human, Plant, and Soil Perspectives
Aula Magna Mangiagalli, Via Commenda 12
Chairs: Francesco LORETO, University of Naples Federico II
Sabrina SARROCCO, University of Pisa
Vittoria CATARA
,
University of Catania
The microbiome as a systemic determinant of plant health.
Giuliano BONANOMI
,
University of Naples Federico II
Modulation of soil and rhizosphere microbiome to improve plant defence and ecosystem functions
Michele PERAZZOLLI
,
University of Trento
Plant-associated microbial communities contribute to abiotic stress resilience
Marco VENTURA
,
University of Parma
The role of bifidobacteria in shaping the human gut microbiotaThe role of bifidobacteria in shaping the human gut microbiota
08.30 – 10.20
PARALLEL SYMPOSIUM 3: Multiscale analysis of brain function and dysfunctions
Aula Magna, Via Festa del Perdono 7
Chairs: Anna FASSIO, University of Genoa
Tommaso FELLIN, Istituto Italiano di Tecnologia
Simona LODATO
,
Humanitas University
Early spontaneous activity shapes neuronal diversity and circuit assembly in the developing cerebral cortex
Nathalie ROCHEFORT
,
University of Edinburgh
Movie-trained transformer model reveals novel response properties to dynamic stimuli in mouse visual cortex
Alessandro GOZZI
,
University of Trento and Italian Institute of Technology
Multiscale Decoding of Functional Brain Maps
Marcello MASSIMINI
,
University of Milan
Cortical dynamics after brain injury: from neurons to networks
10.20 – 10.30
Claudia SCACCABAROZZI
,
Agilent Technologies
From Sample to Insight: Agilent Integrated Technologies for Modern Life Science Research
10.30 – 11.00
Coffee Break
Cortile del Settecento
11.00 – 12.50
PARALLEL SYMPOSIUM 4: RNA in mammals and plants
Aula Magna, Via Festa del Perdono 7
Chairs: Serena VAROTTO, University of Padua
Michela DENTI, University of Trento
Pablo MANAVELLA
,
University of Malaga
Tiny Transposons, Big Effects: How MITEs Organize Chromatin to Shape Gene Expression
Luca CAPRIOTTI
,
Marche Polytechnic University
RNAi: biotechnological strategies for sustainable plant protection
Germano CECERE
,
Institute Pasteur, Paris
Small RNAs in Epigenetic Inheritance: a lesson from worms
Fabiana QUAGLIA
,
University of Naples Federico II
Engineering RNA Delivery: From Nanoparticle Design to Translational Pipelines
12.50 – 13.00
Antonio CASINI
,
Anemocyte
Streamlining mRNA Manufacturing through AMCAP One-Pot Enzymatic Capping
11.00 – 13.00
PARALLEL SYMPOSIUM 5: Germline Pharmacogenetics: From Scientific Evidence to Clinical Implementation
Aula Magna Mangiagalli, Via Commedia 12
Chairs: Chiara PESENTI, Anatomia patologica ASST BERGAMO OVEST, Treviglio
Monica MOZZO, University of Milan
Matteo FLORIS
,
University of Cagliari
Implementing Pharmacogenetics in Italy: National Initiatives and Strategic Priorities
Erika CECCHIN
,
Oncology Reference Center of Aviano
Clinical benefit and utility of pharmacogenetic testing in oncology: from targeted genotyping to the genetic passport
Laura FONTANA
,
University of Milan
Technical approaches for germline pharmacogenetic testing
Massimo GENNARELLI
,
University of Brescia
Pharmacogenetics in psychiatry
13.00 – 14.00
Lunch
Cortile del Settecento
14.00 – 16.00
SYMPOSIUM 6: Transposable and repetitive Elements in evolution and development
Aula Magna, Via Festa del Perdono 7
Chairs: Michele DE BORTOLI, University of Turin
Andrea LUCHETTI, University of Bologna
Didier TRONO
,
École Polytechnique Fédérale de Lausanne
The Endovirome, its epigenetic controllers and the species-specificity of human biology
Josep CASACUBERTA
,
CRAG Barcelona
LTR-retrotransposons, major drivers of genetic variability and key players in genome structure in plants
Maria Assunta BISCOTTI
,
Marche Polytechnic University
Let’s jump: Transposable Elements as drivers of genomic plasticity
Alessio BOATTINI
,
University of Bologna
Dating polymorphic transposable elements in human populations
16.00 – 17.00
FISV Prize
Aula Magna, Via Festa del Perdono 7
Chairs: Chiara TONELLI, FISV President
Chiara ZUCCATO, FISV Scientific Secretary
FISV Young Researchers Award – Winners:
ABBÀ Silvia, ALOISI Sara, GRENZI Matteo, ROSSINI Michela, TRIOZZI Paolo Maria, VENZIN Valentina
17.00 – 18.00
Apericena
Cortile del Settecento
19.00 – 21.00
MINI-SYMPOSIA
MS4: Current trends in biotechnology
Via Festa del Perdono 7 – Room 435
Chairs: Roberto BASSI, Stazione Zoologica Anton Dohrn, Naples
Simone FERRARI, University of Rome La Sapienza
Germán Darío AHUMADA
,
Sant’Anna School of Advanced Studies, Pisa
Arabidopsis in vitro pipeline identified rice endophytic bacteria that promotes growth after submergence.
Nicolò ALBANESE
,
University of Sannio
Engineering and characterization of third-generation CAR-macrophages for solid tumor immunotherapy
Francesca AMODEO
,
University of Turin
Overcoming the silencing of doxycycline-inducible promoters in hiPSC-derived cardiomyocytes
Giulia BARBIERI
,
University of Pavia
Unlocking high-yield extracellular protease production in Bacillus subtilis by targeting the nutrient-responsive interplay between CodY and the stringent response
Roberto CAFERRI
,
University of Verona
Spectral re-design of LHCB proteins for engineering photosynthetic light use efficiency
Pasquale CREANZA
,
University of Urbino Carlo Bo
Development of a novel eco-friendly bioplastic from engineered phaseolin protein
Suleman Khan ZADRAN
,
University of Bologna
A theranostic M13 phage nanoplatform for systematic CD276 targeting in neuroblastoma
MS5: Food and sustainable nutrition
Via Festa del Perdono 7 – Room 517
Chairs: Laura DE GARA, Campus Bio-Medico University Rome
Maria Manuela RIGANO, University of Naples Federico II
Eleonora COMINELLI
,
CNR-IBBA Milan
CRISPR/Cas9-mediated editing of GmSULTR3;3 uncovers a new approach for regulating phytic acid accumulation in soybean
Roméo Arago DOUGUÉ KENTSOP
,
CNR-IBBA Milan
From Nutritional Characterization to Active Packaging: An Integrated Evaluation of Vegetable Sprouts
Ambra Selene PARMAGNANI
,
University of Milan
Plant-derived nanocarriers for next-generation pest control and crop protection
Paolo PESARESI
,
University of Milan
Optimizing Canopy Photosynthesis in Barley: Identifying Optimal Allelic Variants within the BEST-CROP Project
Gerardo PUOPOLO
,
University of Trento
Heat-stable bacterial metabolites for sustainable crop protection: a strategy to enhance food security through reduced pesticide use.
Gianpiero VIGANI
,
University of Turin
Climate-Driven Changes in Mineral Nutrition: Implications for Sustainable Nutrition and Grain Quality in Durum Wheat
Sabrina SARROCCO
,
University of Pisa
Trichoderma gamsii T6085 as a biocontrol agent against Fusarium head blight of wheat: from modes of action to field performance
MS6: Health and disease
Via Festa del Perdono 7 – Room 515
Chairs: Susanna AMBROSIO, University of Naples Federico II
Manuel GENTILUOMO, University of Pisa
Paola CAMPOMENOSI
,
University of Insubria
PRODH shapes tumor cell behavior and macrophage recruitment in lung adenocarcinoma models
Sonia CONI
,
Sapienza University of Rome
A zinc finger–NFATc3–MYC module links intestinal microbiota to colorectal tumorigenesis
Veronica DE GIORGIS
,
University of Piemonte Orientale
Proteomics-guided drug repurposing identifies novel therapeutic candidates in soft-tissue sarcoma
Laura GIANNOTTI
,
University of Salento
Cannabidiol in brain cancer treatment: modulation of NRF2 pathways and autophagy
Rida HAIDER
,
University of Palermo
A human In Vitro gut–brain axis model for genetic and functional evaluation of psychobiotics
Ludovica LOSPINOSO SEVERINI
,
Sapienza University of Rome
Discovery of a new selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment
Michele MENDITTO
,
University of Palermo
Targeting TP53 nonsense mutations by Translational Readthrough: functional rescue of p53 and enhanced chemotherapy sensitivity
19.00 – 21.00
POSTER PRESENTATION
P1: Enviromental, evolutionary and developmental biology
Via Festa del Perdono 7 – Room 433
Chairs: Fabrizio ARANITI, University of Milan
Vittoria BRAMBILLA, University of Milan
Giulia Ave BONO
,
University of Milan
Rice florigenic proteins determine inflorescence architecture and flower fertility
Carla-Marie BRUNET
,
University of Parma
Genomic evidence for reduced close-kin reproduction in captive baboons
Maria Giuseppina CAMPANILE
,
University of Campania Luigi Vanvitelli
Insight into the amino acid sequence of canihuin, a type-1 ribosome inactivating protein from Chenopodium pallidicaule Aellen seeds
Sara CIMINI
,
Campus Bio-Medico University Rome
miR167 and miR530 define conserved and cultivar-specific miRNA networks to salt stress in temperate japonica rice
Corinne DAMIANI
,
University of Palermo
Native endophytic microbial consortia enhance grapevine resilience to drought and heat stress
Giorgia FABBRINI
,
University of Milan
Plant stress in a new light: novel fluorescent indicators to resolve mitochondrial calcium signatures in vivo
Nicolaj JERAN
,
University of Milan
Forever YounGreen: dissecting the staygreen phenotype to enhance barley yield and resilience
Thais HUARANCCA REYES
,
Univeristy of Pisa
Screening of wetland species for future multispecies remediation systems
Simone LANDI
,
University of Naples Federico II
Oxidative pentose phosphate pathway displays multi-layer post-translational regulation in photosynthetic organisms
Beatrice LANDONI
,
University of Milan
Subgenome-specific circadian growth regulation in tropical allopolyploid cotton under temperate conditions
Giacomo MERCURI
,
University of Parma
Gelada (Theropithecus gelada) genomic diversity sheds light on the biogeography of an endemic species of the ethiopian highlands
Erica MICA
,
Università Piemonte Orientale
Genome-wide association mapping of arsenic uptake and transport in rice using germanium oxide phenotyping
Ginevra Marie Eloise PEPPI
,
University of Bologna
Bridging mechanistic and physiological roles of Arabidopsis AKR4C subfamily in nitric oxide signaling and nitrosoglutathione catabolism
Paola PUNZO
,
IBBR-CNR, Portici
The splicing factor DRT111 regulates secondary dormancy induction in Arabidopsis thaliana
Camilla SANGIOVANNI
,
Tor Vergata University of Rome
Population structure and signatures of domestic introgression in Italian wild boar: insights from STRs and functional SNPs
P2: Genetics, epigenetics and chromosome biology
Via Festa del Perdono 3 – Room 104
Chairs: Grazia Daniela RAFFA, University of Rome La Sapienza
Patrizia GUIDI, University of Pisa
Laura BAVAGNOLI
,
IGM-CNR, Pavia
A novel role for hsa-miR-1307-3p in R-loop homeostasis and genome stability.
Nicolò BEDOTTO
,
University of Pavia
Screening the DNA Damage Response pathway for seed quality hallmarks in Oryza sativa
Andrea BERNARDINI
,
University of Milan
Human-specific innovations in the basal transcription machinery: a novel TAF8 isoform increases TFIID assembly complexity in human cells
Mariarita BRANCACCIO
,
University of Naples Federico II
ZSCAN4–Telomerase Axis Activation Drives Genome Stability Programs in Preeclamptic Placenta
Giovanni DI FUSCO
,
University of Naples Federico II
Autophagy affects DNA damage response by modulating KAT5/TIP60 stability
Chiara FIORENTINO
,
University of Naples Federico II
DeXR: estimating X chromosome inactivation skewing from bulk RNA-seq data
Federica IRIS
,
University of Roma Tre
Oxidative stress as a modulator of DNA damage-induced innate immunity: insights into the cGAS-STING pathway
Giorgio MILAZZO
,
University of Bologna
Distinct CoREST complexes control tumor initiation and oncogenic transcription in neuroblastoma
Giorgio PERRELLA
,
University of Milan
Histone Deacetylase Complex 1 coordinates chromatin organization and transcriptional regulation to drive hypocotyl elongation in plants
Costantino PRECIPUO
,
University of Naples Federico II
Dissecting molecular and epigenetic alterations in Preeclampsia through complementary in vitro and ex vivo models
P3: Genomics, proteomics and systems biology
Via Festa del Perdono 3 – Room 109
Chairs: Luigi LUCINI, Catholic University of the Sacred Heart, Piacenza
Francesca SACCO, University of Rome Tor Vergata
Giovanni SCALA, University of Naples Federico II
Fabrizio ARANITI
,
University of Milan
Unveiling the Phytotoxic Mode of Action of Nootkatone in Arabidopsis thaliana: An Integrated Multi-Omics Approach
Lidia AVALLE
,
University of Piemonte Orientale
From co-expression to causality: defining functional hub genes in basal-like breast cancer networks
Eleonora DAVIDE
,
University of Insubria
Genotype-specific changes in protein and metabolite content in wheat spikelet under nutrient and water stress
Davide DE LUCA
,
IFC-CNR, Pisa
Functional characterization of MYC point mutations identified in diffuse large B-cell lymphoma
Eleonora DI VENERE
,
University of Naples Federico II
From centrosome to primary cilium: the emerging role of TRIM8
Giulio FERRERO
,
University of Turin
The cancer-related DSCAM-AS1 lncRNA evolved midway through primate evolution via Transposable Element acquisition.
Monica GALBUSERA
,
University of Milan
Uncovering the role of polyploid giant cancer cells in high-grade serous ovarian cancer: new treatment perspectives
Silvia GIANOGLIO
,
University of Turin
Insights into the biosynthesis of irregular monoterpenoids from a newly identified α-trans-necrodyl diphosphate synthase from Lavandula stoechas subsp. luisieri
Parinaz KHANJANPOOR
,
University of Insubria
Transcriptomic analysis of advanced adenoma and colorectal cancer showed a widespread dysregulation of LINE-chimeric noncoding transcripts
Giorgia MODENINI
,
University of Padua
Transposable elements may contribute to the expression profiles of genes involved in human neurodevelopmental processes
Sabela NIKOLLI
,
IRCCS National Cancer Institute Regina Elena, Rome
Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53/Dicer complex
Emilia PICCIRILLI
,
University of L’Aquila
In vivo pectin breakdown by inducible expression of a fungal polygalacturonase in Arabidopsis as a tool to study subcellular proteome remodelling upon cell wall damage
08.30 – 10.30
SYMPOSIUM 7: Timing and Causes of Life Course Epigenetic modifications
Aula Magna, Via Festa del Perdono 7
Chairs: Giuseppe PASSARINO, Univerisity of Calabria
Giada FRENZILLI, Univerisity of Pisa
Graziano MARTELLO
,
University of Padua
Role of metabolism in the establishment of epigenetic features at early life stages
Wolfang WAGNER
,
Aachen University Medical School
Life-long and aging related modifications of the epigenetic landscape
Fabio COPPEDÈ
,
University of Pisa
Epigenetic effects of emerging pollutants
Annamaria BUSCHINI
,
University of Parma
Industrial hemp as a model plant for the genotoxic and epigenotoxic evaluation of perfluoroalkyl and polyfluoroalkyl substances (PFAS)
10.30 – 11.00
Coffee Break
Cortile del Settecento
11.00 – 13.00
SYMPOSIUM 8: AI in precision medicine
Aula Magna, Via Festa del Perdono 7
Chairs: Giulia PIAGGIO, IRCCS National Cancer Institute Regina Elena
Enrico DE SMAELE, University of Rome La Sapienza
Alberto TRAVERSO
,
IRCCS San Raffaele Hospital
What will it take to bring AI into personalized medicine?
Francesca CORDERO
,
University of Turin
Integrative Multi-Layer Longitudinal Modeling of MRD Trajectories in Clinical Trials
Egidio D’ANGELO
,
University of Pavia
Multiscale modelling and Brain Digital Twins
Fariba TOHIDINEZHAD
,
Erasmus MC Rotterdam
The Landmarks of Multimodal Learning in Medicine
13.00 – 13.30
Best presentation and poster awards
Aula Magna, Via Festa del Perdono 7
13.30 – 14.00
Closing Remarks
Aula Magna, Via Festa del Perdono 7
Posters will be available in your personal My Fisv Area (Posters section), from 21 Sept. to 20 Oct.
P1 – Enviromental, evolutionary and developmental biology
P1.2
Alessia AMETRANO, IBBC CNR Naples
Simulated marine heatwaves reveal epigenetic regulation of the polymeric immunoglobulin receptor gene in Antarctic teleosts
P1.3
Emanuele BOSI, University of Genoa
The resistome of European coastal environments revealed by high-resolution targeted metagenomics in oysters
P1.4
Giulia Ave BONO, University of Milan
Rice florigenic proteins determine inflorescence architecture and flower fertility
P1.5
Carla-Marie BRUNET, University of Parma
Genomic evidence for reduced close-kin reproduction in captive baboons
P1.6
Maria Giuseppina CAMPANILE, University of Campania Luigi Vanvitelli
Insight into the amino acid sequence of canihuin, a type-1 ribosome inactivatingArabidopsis protein from Chenopodium pallidicaule Aellen seeds
P1.7
Maurizio CARNÀ, University of Turin
β-cyclocitral is not required for acclimation to excess light at 25 °C
P1.8
Sara CIMINI, Campus Bio-Medico University Rome
miR167 and miR530 define conserved and cultivar-specific miRNA networks to salt stress in temperate japonica rice
P1.9
Corinne DAMIANI, University of Palermo
Native endophytic microbial consortia enhance grapevine resilience to drought and heat stress
P1.10
Giorgia FABBRINI, University of Milan
Plant stress in a new light: novel fluorescent indicators to resolve mitochondrial calcium signatures in vivo
P1.11
Valerio FOSCHI, Roma Tre University
Modulation of thermospermine metabolism alters xylem architecture and drought resilience in Solanum lycopersicum plants
P1.12
Flavia GRECO, University of Turin
Space worms: adaptation to microgravity and low magnetic field strength
P1.13
Thais HUARANCCA REYES, Univeristy of Pisa
Screening of wetland species for future multispecies remediation systems
P1.14
Simone LANDI, University of Naples Federico II
Oxidative pentose phosphate pathway displays multi-layer post-translational regulation in photosynthetic organisms
P1.15
Beatrice LANDONI, University of Milan
Subgenome-specific circadian growth regulation in tropical allopolyploid cotton under temperate conditions
P1.16
Giacomo MERCURI, University of Parma
Gelada (Theropithecus gelada) genomic diversity sheds light on the biogeography of an endemic species of the ethiopian highlands
P1.17
Erica MICA, Università Piemonte Orientale
Genome-wide association mapping of arsenic uptake and transport in rice using germanium oxide phenotyping
P1.18
Ginevra Marie Eloise PEPPI, University of Bologna
Bridging mechanistic and physiological roles of Arabidopsis AKR4C subfamily in nitric oxide signaling and nitrosoglutathione catabolism
P1.19
Benedetta PIZZICONI, Campus Bio-Medico, University of Rome
Polystyrene nanoplastics uptake and genotype-dependent responses in durum wheat: from hydroponic to soil-grown systems
P1.20
Paola PUNZO, IBBR-CNR, Portici
The splicing factor DRT111 regulates secondary dormancy induction in Arabidopsis thaliana
P1.21
Camilla SANGIOVANNI, Tor Vergata University of Rome
Population structure and signatures of domestic introgression in Italian wild boar: insights from STRs and functional SNPs
P1.23
Ruihan SHEN, University of Turin
KAI2 receptors shape the response to nitrogen limitation and nitrogen use efficiency in tomato
P1.24
Emanuele CAPRA, IBBA-CNR Lodi
PFNA exposure disrupts sperm function and reprograms the epigenome in male rats
P1.25
Nicolaj ERAN, University of Milan
Forever YounGreen: dissecting the staygreen phenotype to enhance barley yield and resilience
P2 – Genetics, epigenetics and chromosome biology
P2.1
Anna Maria Giuseppina POMA, University of L’Aquila
Effects of Polystyrene and Polyethylene Nanoparticles in Human Colorectal Cancer Cells
P2.2
Laura BAVAGNOLI, IGM-CNR Pavia
A novel role for hsa-miR-1307-3p in R-loop homeostasis and genome stability.
P2.3
Nicolò BEDOTTO, University of Pavia
Screening the DNA Damage Response pathway for seed quality hallmarks in Oryza sativa
P2.4
Andrea BERNARDINI, University of Milan
Human-specific innovations in the basal transcription machinery: a novel TAF8 isoform increases TFIID assembly complexity in human cells
P2.5
Vittoria BRAMBILLA, University of Milan
Stem growth in rice is controlled by chromatin remodelling that promotes cell division at the intercalary meristem
P2.6
Mariarita BRANCACCIO, University of Naples Federico II
ZSCAN4–Telomerase Axis Activation Drives Genome Stability Programs in Preeclamptic Placenta
P2.8
Erika CASARI, University of Milano Bicocca
Activation of MRX endonuclease by the Sae2 C-terminus: functional and molecular insights
P2.9
Elisa CIULLA, University of Palermo
DNA G-quadruplexes and nonsense mutations as dual targets for small-molecule-based cancer therapy
P2.10
Elvira CONIGLIO, University of Catania
Cell type-dependent activation of the NRF2-HMOX1 pathway following UVA and UVB irradiation
P2.11
Claudia COSTANZA, University of Palermo
Disruption of the LINC complex compromises DNMT1 dynamics
P2.12
Francesca SPARVOLI, IBBA-CNR
Optimized Whole-Genome Sequencing enables genome-wide mutation discovery in a new EMS-based common bean TILLING platform
P2.13
Giovanni DI FUSCO, University of Naples Federico II
Autophagy affects DNA damage response by modulating KAT5/TIP60 stability
P2.14
Chiara FIORENTINO, University of Naples Federico II
DeXR: estimating X chromosome inactivation skewing from bulk RNA-seq data
P2.15
Marco GNUGNOLI, University of Milano-Bicocca
Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation
P2.16
Martina GRECO, CIBIO University of Trento
The intranuclear protein quality control pathway sequesters excess histone H3 variant Cse4 to prevent chromosomal instability in budding yeast
P2.17
Federica IRIS, University of Roma Tre
Oxidative stress as a modulator of DNA damage-induced innate immunity: insights into the cGAS-STING pathway
P2.18
Sefora MARINO, University of Palermo
Rescuing REP1, RP1 and RPGR expression in Inherited Retinal Diseases (IRDs) models by translational readthrough approach
P2.19
Giannicola MAROTTA, University of Naples Federico II
8-oxodG as a driver of transcription and genome architecture
P2.20
Giorgio MILAZZO, University of Bologna
Distinct CoREST complexes control tumor initiation and oncogenic transcription in neuroblastoma
P2.21
Patrizia GUIDI, University of Pisa
Anti-genotoxic activity of Posidonia oceanica leaf extract in human intestinal Caco-2 cells: implications for human health
P2.22
Giorgio PERRELLA, University of Milan
Histone Deacetylase Complex 1 coordinates chromatin organization and transcriptional regulation to drive hypocotyl elongation in plants
P2.23
Anna PISCONE, University of Naples Federico II
XRCC1 deficiency promotes telomeric chromatin leakage, inflammatory signalling and senescence
P2.24
Costantino PRECIPUO, University of Naples Federico II
Dissecting molecular and epigenetic alterations in Preeclampsia through complementary in vitro and ex vivo models
P2.25
Erica ROSSI, University Roma Tre
Telomerase reverse transcriptase as a modulator of mitochondrial DNA and mitophagy
P2.26
Martina SANTULLI, University of Bologna
YEATS2 defines an E2F3-associated function of the ATAC core complex
P2.27
Esi TACI, University of Milan
Exploring the link between cellular senescence and neurodegeneration using iDISCO on brain organoids
P2.28
Giada FRENZILLI, University of Pisa
Genotoxicity biomarkers as potential predictors of very-long-term COVID-19 clinical sympthoms.
P2.29
Marco BERNASCONI, University of Milan
Transcription controls chromatin-nuclear lamina contacts through distinct Lamin A and LBR tethering mechanisms
P3 – Genomics, proteomics and systems biology
P3.1
Federica AMORUSO, University of Milano
Integrated CHARGE syndrome models reveal epigenetic modulators of reproductive phenotypes
P3.2
Fabrizio ARANITI, University of Milan
Unveiling the Phytotoxic Mode of Action of Nootkatone in Arabidopsis thaliana: An Integrated Multi-Omics Approach
P3.3
Lidia AVALLE, University of Piemonte Orientale
From co-expression to causality: defining functional hub genes in basal-like breast cancer networks
P3.4
Alessia CANEVOTTI, SEMM European School of Molecular Medicine, Milan
An integrative evidence framework and interactive resource for annotating the human pre-miRNA repertoire
P3.5
Eleonora DAVIDE, University of Insubria
Genotype-specific changes in protein and metabolite content in wheat spikelet under nutrient and water stress
P3.6
Davide DE LUCA, CNR Pisa
Functional characterization of MYC point mutations identified in diffuse large B-cell lymphoma
P3.7
Eleonora DI VENERE, University of Naples Federico II
From centrosome to primary cilium: the emerging role of TRIM8
P3.8
Guido DOMINGO, University of Insubria
Small peptides, big defense: chloroplast non-conventional peptides as novel regulators of thermal stress
P3.9
Giulio FERRERO, University of Turin
The cancer-related DSCAM-AS1 lncRNA evolved midway through primate evolution via Transposable Element acquisition.
P3.10
Margherita FERRETTI, IRCCS National Cancer Institute Regina Elena Rome
Spontaneous miscarriage reveals CD47-SIRPa axis as a targetable immune checkpoint in endometrial cancer
P3.11
Monica GALBUSERA, University of Milan
Uncovering the role of polyploid giant cancer cells in high-grade serous ovarian cancer: new treatment perspectives
P3.12
Silvia GIANOGLIO, University of Turin
Insights into the biosynthesis of irregular monoterpenoids from a newly identified α-trans-necrodyl diphosphate synthase from Lavandula stoechas subsp. luisieri
P3.13
Parinaz KHANJANPOOR, University of Insubria
Transcriptomic analysis of advanced adenoma and colorectal cancer showed a widespread dysregulation of LINE-chimeric noncoding transcripts
P3.14
Sophia LUCHE, University of Parma
Functional dynamics: metabolomic exploration of perennial wheat roots and their interacting microbial ecosystem
P3.15
Marcello MANFREDI, University of Piemonte Orientale
Unraveling CSF protein complex networks in neurodegenerative diseases
P3.16
Stefania MARTUCCIELLO, University of Salerno
Vegfr3 is required in the Tbx1 expression domain for cardiac outflow tract development.
P3.17
Giorgia MODENINI, University of Padova
Transposable elements may contribute to the expression profiles of genes involved in human neurodevelopmental processes
P3.18
Sabela NIKOLLI, IRCCS National Cancer Institute Regina Elena, Rome
Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53/Dicer complex
P3.19
Emanuela PEDRAZZINI, IBBA-CNR Milan
Lysine deserts in seed storage protein evolution
P3.20
Davide PEZZINI, University of Pavia
Multi-omics approach to investigate the impact of seed coat pigmentation on Trifolium alexandrinum germination
P3.21
Emilia PICCIRILLI, University of L’Aquila
In vivo pectin breakdown by inducible expression of a fungal polygalacturonase in Arabidopsis as a tool to study subcellular proteome remodelling upon cell wall damage
P3.22
Shraddha SHRIDHAR GAONKAR, University of Pavia
Metabolomic and ionomic changes mediated by antioxidant compounds in Populus nigra seeds
P4 – Current trends in biotechnology
P4.1
Germán Darío AHUMADA, Sant’Anna School of Advanced Studies, Pisa
Arabidopsis in vitro pipeline identified rice endophytic bacteria that promotes growth after submergence.
P4.2
Nicolò ALBANESE, University of Sannio
Engineering and characterization of third-generation CAR-macrophages for solid tumor immunotherapy
P4.3
Francesca AMODEO, University of Turin
Overcoming the silencing of doxycycline-inducible promoters in hiPSC-derived cardiomyocytes
P4.4
Giulia ANDERLUZZI, University of Milan
The effect of cationic polymer on the structure and pDNA transfection efficiency of lipopolyplexes
P4.5
Giacomo BIRRO, University of Verona
Primed for stress: loss of Aucsia2 improves salt resilience in tomato
P4.6
Michela BRUSCHI, University of Urbino Carlo Bo
Thiol-based compound hinders Pseudomonas aeruginosa pyocyanin redox cycling and dampens LPS-driven acute pulmonary inflammation
P4.7
Roberto CAFERRI, University of Verona
SPECTRAL RE-DESIGN OF LHCB PROTEINS FOR ENGINEERING PHOTOSYNTHETIC LIGHT USE EFFICIENCY
P4.8
Simona COMPARATO, Istituto Nazionale Oncologico Candiolo
Exploring the expression pattern of LINE-1–derived chimeric transcript of MET (L1-MET) across different tumor types
P4.9
Pasquale CREANZA, University of Urbino Carlo Bo
Development of a novel eco-friendly bioplastic from engineered phaseolin protein
P4.10
Marco DAINELLI, University of Florence
Constitutive metabolic adjustments underlying thallium hyperaccumulation in Silene latifolia
P4.11
Antimo DI MARO, University of Campania Luigi Vanvitelli
Celosin, a novel type-1 ribosome inactivating protein isolated from Celosia argentea L. seeds, demonstrates significant antiviral activity against coronaviruses in vitro
P4.12
Giulia BARBIERI, University of Pavia
Unlocking high-yield extracellular protease production in Bacillus subtilis by targeting the nutrient-responsive interplay between CodY and the stringent response
P4.13
Francesca GIANNESE, Human Technopole, Milan
The National Facility for Genomics of Human Technopole: Supporting Population Genomics Research and Technology Development in Italy
P4.14
Maria Raffaella BALESTRINI, CNR
Dissection of genotype-dependent grapevine responses to arbuscular mycorrhizal symbiosis
P4.15
Rita LOTRECCHIANO, University of Sannio
Extremely low- frequency electromagnetic stimulation as a non-invasive tool for modulating bacterial biofilms
P4.16
Elisa MARICCHIOLO, University of Urbino Carlo Bo
A new biotechnological platform for controlled anthocyanin biosynthesis via Sn overexpression in carrot callus cultures
P4.17
Mariagrazia MARTINI, University of Sannio
Effects of Extremely Low-Frequency Electromagnetic Fields on Wnt-Mediated Cardiac Differentiation of Human Induced Pluripotent Stem Cells
P4.18
Giovanni MESSINA, Link Campus University, Rome
Setting up of an in vitro model to investigate the effects on cell metabolism induced by the photobiomodulation protocols used for plantar fasciopathy
P4.19
Pietro ROVERSI, CNR-IBBA Milan
Structural Basis of ERAD-L Commitment by an EDEM:PDI Checkpoint Complex
P4.20
Maria SCRASCIA, University of Bari Aldo Moro
Polyurethane degrading bacteria isolates from plastic landfill: in vitro assays on solid and liquid media
P4.21
Suleman Khan ZADRAN, University of Bologna
A theranostic M13 phage nanoplatform for systematic CD276 targeting in neuroblastoma
P5 – Food and sustainable nutrition
P5.1
Emma BERTOLE’, University of Milan
Set up method for assessing the amount and activity of wheat germ agglutinin lectin
P5.2
Lorenzo BRUSETTI, Free University of Bolzano
Irrigation water quality drives antimicrobial resistance co-selection along the Adige Valley: preliminary findings from the AppleHealth project
P5.3
Beatrice CHIAVACCI, University of Florence
Crops that inherit their stress memories: Cicer arietinum against salt stress
P5.4
Eleonora COMINELLI, CNR-IBBA Milan
CRISPR/Cas9-mediated editing of GmSULTR3;3 uncovers a new approach for regulating phytic acid accumulation in soybean
P5.5
Elena DE AMICIS, University of L’Aquila
Microalgal bioactive compounds as natural elicitors for sustainable crop protection
P5.6
Noemi DI VITA, University of Padova
Proof of concept for RNAi-based weed control in Solanum nigrum
P5.7
Ridwan DIAGUNA, University of Pavia
Screening for heat stress tolerance in tomato: Impact on seed repair response
P5.8
Roméo Arago DOUGUÉ KENTSOP, CNR-IBBA Milan
From Nutritional Characterization to Active Packaging: An Integrated Evaluation of Vegetable Sprouts
P5.9
Alessandra MARINELLI, University of Milan
Anthocyanins as a possible strategy to protect against mycotoxin toxicity
P5.10
Andrea PAGANO, University of Pavia
Synergies in seed quality research to enhance stress tolerance in model and orphan legumes
P5.11
Ambra Selene PARMAGNANI, University of Milan
Plant-derived nanocarriers for next-generation pest control and crop protection
P5.12
Paolo PESARESI, University of Milan
Optimizing Canopy Photosynthesis in Barley: Identifying Optimal Allelic Variants within the BEST-CROP Project
P5.13
Gerardo PUOPOLO, University of Trento
Heat-stable bacterial metabolites for sustainable crop protection: a strategy to enhance food security through reduced pesticide use.
P5.14
Gianpiero VIGANI, University of Turin
Climate-Driven Changes in Mineral Nutrition: Implications for Sustainable Nutrition and Grain Quality in Durum Wheat
P5.15
Maria Manuela RIGANO, University of Naples Federico II
Effect of combined shade and drought stress on a S. pennellii introgression line.
P5.16
Sabrina SARROCCO, University of Pisa
Trichoderma gamsii T6085 as a biocontrol agent against Fusarium head blight of wheat: from modes of action to field performance
P5.17
Marta TOCCACELI, University of Milan
Purple corn anthocyanins encapsulated in zein nanoparticles and their role against inflammatory bowel diseases in vitro
P6 – Health and disease
P6.1
Giulia Luna BERGANTINO, University of Sannio
Selection of DNA aptamers targeting psoriasis-associated CARD14-mutant keratinocytes
P6.2
Stefano BIRESSI, University of Trento
Reduced fibrosis after in vivo inhibition of complement C1 in animal models of Duchenne Muscular Dystrophy
P6.3
Paola CAMPOMENOSI, University of Insubria
PRODH shapes tumor cell behavior and macrophage recruitment in lung adenocarcinoma models
P6.4
Ludovica CAPONE, University of Sannio
Disruption of macrophage CBM complex signaling impairs adipocyte metabolic homeostasis in vitro.
P6.5
Sonia CONI, Sapienza University of Rome
A zinc finger–NFATc3–MYC module links intestinal microbiota to colorectal tumorigenesis
P6.6
Maria Rosaria COSCIA, National Research Council
Immune adaptations to acute and chronic hypobaric hypoxia: molecular insights from Antarctic and simulated environments
P6.7
Veronica DE GIORGIS, University of Piemonte Orientale
Proteomics-guided drug repurposing identifies novel therapeutic candidates in soft-tissue sarcoma
P6.8
Rosita DI PALMA, University of Naples Federico II
Targeting oxidative and ER stress to improve chemotherapy in lung cancer cell: the adjuvant role of olea europaea in lung cancer
P6.9
Chiara DONATI, University of Pavia
Novel Riluzole-derivative VA942 affects voltage-gated sodium and potassium currents expressed in SH-SY5Y-derived neurons
P6.10
Laura GIANNOTTI, University of Salento
Cannabidiol in brain cancer treatment: modulation of NRF2 pathways and autophagy
P6.11
Rida HAIDER, University of Palerrmo
A human In Vitro gut–brain axis model for genetic and functional evaluation of psychobiotics
P6.12
Ludovica LOSPINOSO SEVERINI, Sapienza University of Rome
Discovery of a new selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment
P6.13
Federico MANAI, University of Pavia
TET2 dysregulation identifies genomically unstable and prognostically relevant subgroups in high-grade serous ovarian carcinoma
P6.14
Nicole MARCATI, University of Parma
Parallel Evolution of a GLP1R Residue in Mammals and Humans Reveals a Pharmacogenomic Determinant of GLP-1 Receptor Agonist Response
P6.15
Valentina MARGARITA, University of Sassari
Sex-based differences in prenatal innate immunity: divergent foetal responses to Mycoplasma hominis infection between males and females
P6.16
Michele MENDITTO, University of Palermo
Targeting TP53 nonsense mutations by Translational Readthrough: functional rescue of p53 and enhanced chemotherapy sensitivity
P6.17
Francesco ACQUATI, University of Insubria
Role of the human RNASET2 gene in the pathogenesis of Aicardi-Goutières syndrome.
P6.18
Shirin NAVACCI, Sapienza University of Rome
AMBRA1 regulates Sonic Hedgehog signaling during cerebellar development and promotes SHH-medulloblastoma
P6.19
Roberto OLEARI, University of Milan
Connecting craniofacial malformations with neural crest splicing defects by defining the role of nuclear cyclophilin NKTR
P6.20
Zeudi PETRONE, University of Naples Federico II
Modelling diabetic corneal injury in ovo: a rapid platform for testing bioactive ophthalmic formulations
P6.21
Valentina POZZI, Polytechnic University of Marche
The role of catechol-o-methyltransferase dysregulation in human urothelial carcinoma development
P6.22
Davide SARTINI, Marche Polytechnic University
Therapeutic potential of paraoxonase-2 enzyme in triple-negative breast cancer treatment
P6.23
Chiara SCAPOLI, University of Ferrara
Recurrent pregnancy loss and smoking share CTNNA2 rs4852592 locus effects through independent pathways
P6.24
Gabriele SALES, University of Padova
Self-supervised learning reveals mutation-specific morphological signatures in Gaucher disease fibroblasts
